The Essential Role of Glutathione in Health
Glutathione is a powerful antioxidant naturally present in every human cell, playing a critical role in protecting cells by neutralizing free radicals. Without adequate glutathione, cells are more vulnerable to damage, and depletion can lead to cell death. It is particularly vital for skin, lens, retina, and cornea health and acts as a cofactor in numerous bodily processes, serving as a foundational component in the liver, kidneys, lungs, intestines, and other organs’ detoxification pathways. Extensive scientific research shows that glutathione levels directly impact cell health and function.
Glutathione and Parkinson’s Disease
Glutathione deficiencies have been linked to various diseases, especially neurodegenerative conditions like Parkinson’s disease. Parkinson’s involves dopamine loss in the brain’s substantia nigra region, where glutathione depletion is one of the earliest indicators. Low glutathione levels increase free radical activity, accelerating disease progression. Mitochondrial cells—essential for energy production—are particularly sensitive to glutathione shortages, and when levels fall below 70%, these cells can die, contributing to mitochondrial dysfunction closely linked to Parkinson’s. Clinical studies indicate that intravenous (IV) glutathione therapy can improve symptoms such as rigidity, posture, gait, speech, and decreased movement. At our Center for Integrative Medicine, we offer IV glutathione therapy customized to each patient’s needs, with typical doses for Parkinson’s adjunctive treatment ranging from 2-3 grams per infusion.
Additional Uses of Glutathione Therapy
Some individuals cannot produce sufficient glutathione due to genetic factors, leading to neurological or blood-related issues. Glutathione deficiency is also common among patients with HIV/AIDS, liver cirrhosis, hepatitis, and lung conditions like COPD, asthma, and fibrosis. Elderly individuals, people with digestive disorders like gastritis and inflammatory bowel disease, diabetes, and pancreatic inflammation also often experience altered glutathione levels. As we age, glutathione levels naturally decline, impacting cellular function. Research continues to reveal new disease connections with glutathione deficiency, and supplementation is proving to be a valuable therapeutic strategy.
Safety and Scheduling Your Appointment
Glutathione therapy is generally safe; however, it’s essential to consult a licensed healthcare provider before beginning supplementation, particularly for those with sulfite sensitivities or patients undergoing chemotherapy.
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To learn how Longiva IV glutathione therapy could benefit your health and well-being. References: Gaby, A.R., Nutritional Medicine, Fritz Perlberg Publishing, 2011 “Glutathione, Reduced (GSH),” Alt Med Rev, 2001;6(6):601-607 Schulz, J.B., et al. “Glutathione, oxidative stress and neurodegeneration,” Eur J Biochem, 2000;267:4904-4911 Sechi, G., et al. “Reduced intravenous glutathione in the treatment of early Parkinson’s disease,” Prog Neuropsychopharmacol Biol Psychiatry, 1996;20:1159-1170 Venkateshappa, C., et al. “Increased oxidative damage and decreased antioxidant function in aging human substantia nigra compared to striatum,” Neurochem Res, 2011
